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PREGNANCY AND DEET (N,N-diethylmetatoluamide)

 
Considerations for the West Nile Virus Season:    
  • With the emergence of the West Nile Virus and the potential of infection from mosquito bites, personal protection with the application of DEET containing products are recommended for people over 6 months of age.

  • There have been no human studies in the first trimester of pregnancy demonstrating the safety of DEET in the effective concentrations of 20 –30%.

  • Certain studies during the second and third trimesters have shown that DEET is absorbed systemically, crosses the placenta and deposits in fetal tissue in small concentrations – with no fetal ill effects mentioned.

  • Based on the limited research, there have been no recommendations from Health Canada or Motherisk re: the use of DEET in pregnancy.

  • The Centre for Disease Control and Prevention: Health Information for International Travel 2003-2004 states that the recommendations for DEET use in pregnant women does not differ from those for non-pregnant adults.

  • Breastfeeding – DEET has not been reported to cause problems in nursing babies. Ensure that skin and hands are well cleansed before feeding.

  • During Pregnancy- the alternate measures to minimize exposure are advised:

      • use the lowest percentage of DEET products possible for effective  protection and wash skin with soap and water immediately upon returning indoors and /or

      • protection is no longer needed.

      •  minimize exposure to bites by limiting outdoor activity from dusk to dawn

      • wear light coloured clothing, long sleeve shirts and long pants, tuck pants into socks and button shirt cuffs for extra protection  
                
      • eliminate mosquito breeding grounds to keep their numbers down

      • assess the level of risk of exposure versus the risk of adverse effects during pregnancy and use the guidelines outlined in the DEET Application Chart shown below:

Age

Applications
Per Day

DEET
Concentration

Comments

Under 6 months

0

0

DEET should not be used on infants under 6 months

6 months to 2 years

1

10% or less

Apply only if a high risk of infection exists

2 to 12 years

3 maximum

10% or less

Avoid face and hands

Over 12 years

As required

30% or less

Avoid face and hands

 

 

References:

American Journal of Tropical Medicine 2001 Oct;65(4): 285-9 – Safety of the Insect Repellent N,N-diethylmetatoluamide (DEET) in Pregnancy.

Canadian Medical Association Journal 2003;Aug 169 (3)  Online 1-4 – DEET-based insect repellents: safety implications for children and pregnant and lactating women.

Health Information for International Travel 2003-2004. Department of Health and Human Services Centres for Disease Control and Prevention.

MMWR 2004 Feb Vol 53, No 7 154-7 – Interim Guidelines for the Evaluation of Infants Born to Mothers Infected with West Nile Virus During Pregnancy.

Region of Waterloo Public Health “Fight the Bite”

Reproductive Toxicology 1992; 6(2): 175-6 Intrauterine diethylmetatoluamide  exposure and fetal outcome. Shaefer C, Peters PW

 

Adapted from : Region of Waterloo Public Health

 

 

 

Tuesday, March 18, 2008 11:06:46 AM


 
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